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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of fungal keratitis
ncRNA name TSLP siRNA
ncRNA Category siRNA
Disease name fungal keratitis
Species Homo sapiens
Tissues/Cell_line transformed human corneal epithelial cells (THCECs)
Methods siRNA transfection, RT-PCR, ELISA
Expression pattern associated
Functional description When TSLP was suppressed by siRNA, fungal keratitis was mild with higher levels of antimicrobial peptides such as human beta-defensin (hBD9).
PubMed ID 30853520
Year 2019
Title Interactions of thymic stromal lymphopoietin with TLR2 and TLR4 regulate anti-fungal innate immunity in Aspergillus fumigatus-induced corneal infection.
Drug-related ncRNA NO

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